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Pipeline surveillance

The active drug pipeline can be a key challenge for payors seeking to balance member coverage and cost. CVS Caremark’s pipeline surveillance and insights can help you stay ahead in a rapidly changing marketplace.

CVS Caremark’s Clinical Pipeline Services team provides market intelligence on drugs in development. This group of licensed clinical pharmacists and analysts has extensive experience and knowledge in clinical practice, the drug regulatory process and the business implications of emerging therapeutic entities.

Our clinical expertise, industry surveillance and reporting tools can help inform management decisions, contain rising costs and achieve lower overall drug trend. We monitor drugs in development and key breakthrough therapies in order to project trend, cost and utilization.

Gene and genetically modified cellular therapies, for example, have the potential to effectively cure diseases that once were incurable, though they come with an extraordinarily high price tag. Single-dose treatments can cost millions, and the clinical scope is widening. Proactive ongoing surveillance of the gene therapy pipeline can help inform coverage decisions and help plan sponsors prepare for the financial impact.

  • Q2 2025 Pipeline Drugs to Watch Report

    See what’s in the near-term specialty and non-specialty pipeline, including a breakthrough therapy for non-small cell lung cancer and biosimilars to Prolia and Xgeva. 

  • Q1 2025-Q4 2027 Gene Therapy Report

    Get a three-year outlook on anticipated gene therapies, including new cancer treatments and a therapy for macular degeneration that could benefit millions. 

2025-2027 anticipated robust pipeline3

  • 334 new specialty drugs
  • 238 supplemental specialty indications
  • 29 gene therapy products

Quarterly pipeline reports include drug-level profiles, insight into trend drivers and specific guidance. We have robust dashboards that generate population insight, identify top drug and utilization trends, model budget impact and show year-over-year trend data.

2024 approvals

84

supplemental specialty indications

65

total novel approvals

50

CDER approvals1

19

biosimilars approved2

Featured solutions

Gene therapy stop-loss

Balancing access, coverage and affordability for breakthrough therapeutics

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Biosimilars

Competition that drives to low net cost

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Let’s work together to find your lowest net costs