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Pipeline surveillance

The active drug pipeline can be a key challenge for payors seeking to balance member coverage and cost. CVS Caremark’s pipeline surveillance and insights can help you stay ahead in a rapidly changing marketplace.

CVS Caremark’s Clinical Pipeline Services team provides market intelligence on drugs in development. This group of licensed clinical pharmacists and analysts has extensive experience and knowledge in clinical practice, the drug regulatory process and the business implications of emerging therapeutic entities.

Our clinical expertise, industry surveillance and reporting tools can help inform management decisions, contain rising costs and achieve lower overall drug trend. We monitor drugs in development and key breakthrough therapies in order to project trend, cost and utilization.

Gene and genetically modified cellular therapies, for example, have the potential to effectively cure diseases that once were incurable, though they come with an extraordinarily high price tag. Single-dose treatments can cost millions, and the clinical scope is widening. Proactive ongoing surveillance of the gene therapy pipeline can help inform coverage decisions and help plan sponsors prepare for the financial impact.

  • Q2 2026 Pipeline Drugs to Watch Report

    See which therapies are lined up for possible approval next quarter, including another oral GLP‑1 and a potential new treatment for severe hypertriglyceridemia.

  • Q1 2026-Q4 2028 Gene Therapy Report

    Explore new gene therapies moving closer to reality, from treatments for hearing loss to one-time administered options for rare metabolic disorders.

2026-2028 anticipated robust pipeline*

  • 367 anticipated novel drug approvals
  • 266 supplemental indications
  • 41 new biosimilars*

Quarterly pipeline reports include drug-level profiles, insight into trend drivers and specific guidance. We have robust dashboards that generate population insight, identify top drug and utilization trends, model budget impact and show year-over-year trend data.

2025 approvals*

87

supplemental specialty indications

58

total novel approvals

46

Center for Drug Evaluation and Research (CDER) approvals

Let’s work together to find your lowest net costs

 

  • *FOR 2026–2028 ANTICIPATED SPECIALTY AND NON-SPECIALTY PIPELINE: CVS Caremark Clinical Pipeline Services projections, data 2026 through 2028, as of February 2026. New drug count includes new molecular entities, new biologics, biosimilars, new combinations, new formulations, CAR-T and non-CAR-T projections by Pipeline Services.

  • * FOR 41 NEW BIOSIMILARS: https://www.fda.gov/drugs/biosimilars/biosimilar-product-information 

  • * FOR 2025 APPROVALS: https://www.fda.gov/media/190705/download